BPH 80110 B. Pharmacy Examinations – May, 2015 (VIII Semester – Regulation 2010-11) Paper – I : Pharmaceutical Chemistry – V (Natural Products) Time: Three hours

Maximum Marks: 70 SECTION-A – (4 x 10 = 40 marks) Answer any FOUR questions

SECTION-A (4x10=40 M) Answer any FOUR Questions 1. Write in detail about chemistry and uses of cardiac glycosides? 2. Classify amino acids with their structures and discuss in detail about chemistry of oxytocin? 3. Write a note on chemistry and biological significance of citral? Give the structures of geraniol, limonene, menthol and α-terpineol? 4. Give the structural elucidation of papaverine with suitable reactions? 5. Discuss about chemistry of bile acids. Give the interrelationship reactions between estradiol, estrone and estriol? 6. Classify vitamins, discuss about chemistry and structural features of ascorbic acid? SECTION-B Answer any TEN Questions

(10x3=30 M)

7. Write a note on disaccharides? 8. Write about qualitative tests for proteins and amino acids? 9. Classify proteins and give the general properties of proteins? 10. What is isoprene and special isoprene rules? 11. Write a note on flavonoids? 12. Give the specific identification tests for tropane alkaloids and xanthine alkaloids? 13. Write the general extraction procedure for alkaloids? 14. Mention about biosynthesis of bile acids from cholesterol? 15. Give the synthesis of progesterone? 16. Give a note on sex hormones? 17. Write about water soluble vitamins? 18. Give the structures of glucose, ergosterol, estrone, cortisone and riboflavin?

BPH 80310 B. Pharmacy Examinations – May, 2015 (VIII Semester – Regulation 2010-11) Paper – III : Pharmacognosy-II Time: Three hours

Maximum Marks: 70 SECTION-A – (4 x 10 = 40 marks) Answer any FOUR questions

1. Write about the biological source, cultivation, collection, constituents and uses of Senna. 2. Give an account of the following drugs: (a) Cinchona (b) Ergot 3. Write about the following: (a) Fennel (b) Clove 4. Describe the applications of plant tissue culture in the production of pharmaceutically important secondary metabolites. 5. Write biological source, chemical constituents and uses of (a) Amla (b) Punarnava 6. Write an account of : (a) Castor oil (b) Shark liver oil

SECTION-B Answer any FOUR questions 7. Write the chemical tests for identifying Digitalis. 8. Mention the chemical constituents of Ginseng. 9. Write the uses of Withania. 10. Mention the chemical constituents of Colchicum. 11. Write the chemical constituents and uses of Musk. 12. Write the source and chemical constituents of Peppermint. 13. Write about growth pattern of suspension of culture. 14. Mention the types of cultures & their merits 15. Write the Chemical constituents of Kantkari. 16. Write the Source and uses of Sataver. 17. Write the Source and constituents of Wool fat. 18. Write the uses of Hydnocarpus oil and Cocoa butter.

(10x3=30 M)

BPH 80510 B. Pharmacy Examinations – May, 2015 (VIII Semester – Regulation 2010-11) Paper – III : Good Manufacturing Practices & Validation Time: Three hours

Maximum Marks: 70 Section-A Answer any Four questions

4x10=40M

1. Explain GMP requirements for plant and equipment. 2. Write in detail about different types of validation. 3. Discuss in detail validation method for water for injection. 4. Describe the calibration procedure for HPLC. 5. What are different types of sampling techniques? Add a note on control charts. 6. Write about organizational structure of ICH. Explain the significance of GLP.

Section-B Answer any Ten questions

3x10=30M

7. Mention the significance of cGMP. 8. Write a short note on reference standards. 9. Discuss the parameters in analytical method validation. 10. What are the types of equipment validation? 11. Write the validation procedure for distilled water. 12. Write about complaint records. 13. Discuss the importance of calibration. 14. Give a brief note on calibration of UV-Visible spectrophotometer. 15. What are the benefits of statistical quality control? 16. Explain computer applications in GMP and GLP. 17. What is purpose of SOP’s? 18. What are the advantages of ISO-9000?