11/5/13

CDC - Sickle Cell Disease, Recommendations - NCBDDD

Recommendations

Health Supervision for Children with Sickle Cell Disease From the American Academy of Pediatrics (AAP), 2002 This statement provides pediatricians in primary care and subspecialty practice with an overview of the genetics, diagnosis, clinical manifestations, and treatment of SCD. Specialized comprehensive medical care decreases morbidity and mortality during childhood. The provision of comprehensive care is a time­intensive endeavor that includes ongoing patient and family education, periodic comprehensive evaluations and other disease­specific health maintenance services, psychosocial care, and genetic counseling. Timely and appropriate treatment of acute illness is critical, because life­threatening complications develop rapidly. It is essential that every child with SCD receive comprehensive care that is coordinated through a medical home with appropriate expertise. Read more about this statement » (http://aappolicy.aappublications.org/cgi/content/full/pediatrics;109/3/526)  (http://www.cdc.gov/Other/disclaimer.html)

The Management of Sickle Cell Disease From the National Heart Lung and Blood Institute (NHLBI), 2002 The practice guidelines best supported by scientific evidence are: Penicillin prophylaxis prevents pneumococcal sepsis in children Pneumococcal vaccine prevents pneumococcal infection in children In surgical settings, simple transfusions to increase hemoglobin (Hb) levels to 10 g/dL are as good as or safer than aggressive transfusions to reduce sickle hemoglobin (Hb S) levels to below 30 percent Transfusions to maintain a hematocrit of more than 36 percent do not reduce complications of pregnancy Transfusions to reduce Hb S levels to below 30 percent prevent strokes in children with high central nervous system blood flow Hydroxyurea decreases crises in patients with severe sickle cell disease

www.cdc.gov/ncbddd/sicklecell/recommendations.html

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11/5/13

CDC - Sickle Cell Disease, Recommendations - NCBDDD

Read more about these practice guidelines »  (http://www.nhlbi.nih.gov/health/prof/blood/sickle/sc_mngt.pdf)  (http://www.cdc.gov/Other/disclaimer.html)

Problem Oriented Clinical Guidelines From the Sickle Cell Information Center, 1991 These protocols are guidelines in use at the Sickle Cell Center at Grady Health System, and they are intended for use by heath care providers treating patients with sickle cell syndromes. These guidelines supplement to current texts in general medicine, surgery and pediatrics. These guidelines address more than 40 specific issues, such as abdominal pain, congestive heart failure, and infections. Read more about these guidelines » (http://www.scinfo.org/prod04.htm)  (http://www.cdc.gov/Other/disclaimer.html)

Related Pages Healthcare Providers (/ncbddd/sicklecell/hcp.html) Blood Disorders (/ncbddd/hbd) Newborn Screening (/newbornscreening) Genomics (/genomics) Minority Health (/omhd) National Center on Birth Defects and Developmental Disabilities (/ncbddd/index.html) Page last reviewed: January 21, 2010 Content source: Centers for Disease Control and Prevention

Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA 800­CDC­INFO (800­232­4636) TTY: (888) 232­6348 ­ Contact CDC­INFO

www.cdc.gov/ncbddd/sicklecell/recommendations.html

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