EFFECT OF NON-IONIZING ELECTROMAGNETIC RADIATION AT MOBILE PHONE FREQUENCY ON HUMAN THYROID CELLS Hilly, Ohad1; Silva, Verónica2; Mizrachi, Aviram1; Ariel, Ortal2; Raiter, Annat2; Hauptman, Yirmi3; Hardy, Britta2; Feinmesser, Raphael1 1 Otolaryngology Head and Neck Surgery, Rabin Medical Center, Petah Tikva, Israel; 2Felsenstein Medical Research Center, Tel Aviv University, Tel Aviv, Israel; 3Gal Safe Ltd., Or Yehuda, Israel Background/Purpose: The aim of this study was to examine the effect of non-ionizing electromagnetic radiation (NIER) at mobile phone frequency on human thyroid cells. Methods: We cultured samples of normal thyroid tissue and subsequently exposed the cultured thyrocytes to NIER for 3 hours. NIER effects were evaluated in terms of proliferation using a cell viability assay and immunohistochemistry. Results: We found that NIER exposure for 3 hours has lead to an increased proliferation of thyrocytes in cell viability assay (p=0.007). This result was confirmed by immunohistochemistry with antibodies against Ki67. Discussion & Conclusion: In this study we present for the first time an in vitro evaluation of NIER effects on human thyroid cells. Our results suggest a proliferative effect of NIER on human thyrocytes, an effect that may link NIER exposure with potential carcinogenesis.
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discussions. This research was supported by the. United States Army Research Office (USARO) through grants W911NF-07-1-034 and 50342-PH-. MUR, the National Science Foundation (NSF) through grant DMS-050989, and the Russian. Foundation for Basic Resea