J6U1/8A16 Reg. No St. Joseph’s college f Arts & Science (Autonomous) St. Joseph’s College Road, Cuddalore – 607001 EBC613- ENDOCRINOLOGY Time : 3 hrs

Max Marks :75

SECTION – A (25X1=25) Answer ALL the questions I choose the best answer: (10X1=10) 1. Amino acid derivatives is a) Insulin

b) Glucocorticoids

c) Thyroxine d) Estrogens

2. Hormone that binds to intracellular receptor a)Estrogens

b)Adreno carticotropic hormone(ACTH)

c) Gastrin d) Oxytocin 3. Adrenocorticotropic hormone secreted by anterior pituitary acting through a) cGMP

b) Calcium

c) cAMP

d) all the above

4. Oxytocin produced by a) Anterior pituitary b) Posterior pituitary c) Pancreas

d) None of the above

5. Hypothalamus produces a) thyrotrophic-releasing hormone b) Corticotrophin releasing Hormone c) Gonadotropin releasing hormone d) All the above 6. Excessive production of which hormone causes Gigantism in children a)Growth Hormone

b)insulin

c) Human chorionic gonadotropin d) ACTH 7. Hyperthyroidism is caused by a) Goiter

b) Grave's disease

c) Thyrotoxicosis d) cretinism

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J6U1/8A16 8. Total amino acids present in both chain of insulin is a) 21 b) 30 c) 51 d) 86 9. Hormones of Adrenal medulla a) Epinephrine b) TSH c) Aldosterone d) glucagon 10. Which hormone involved in the reproductive process in women a) Testosterone

b) Estrogen c) androgens

d) all the above

II. Say true or false (5X1=5) 11. All the Hormones are proteins. 12. The second messenger of Growth Hormone is cAMP. 13. TRH stimulates anterior pituitary to release thyroid stimulating hormone. 14. Abnormal increase in the size of the thyroid gland is known as goiter. 15. Estrogens do not increase lipogenesis in adipose tissues. III. Answer all the questions

(10X1=10)

16. List any two hydrophilic hormones. 17. What is feedback regulation? 18. Where is HRE (hormone response elements) present? 19. Give the list hormones acting through cAMP as a second messenger. 20. What is D A G? 21. Which hormone regulates the water salt balance in our body? 22. What is the hormone produced by human placenta? 23. Which hormone reduces the renal excretion of calcium? 24. Give the main function of rennin - angiotensin. 25. What is pheochromocytoma?

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J6U1/8A16 SECTION -B (4X5=20) Answer any FOUR of the following: 26. Write the chemical classification of hormone with suitable examples. 27. Explain calcium is a mediator of hormone action. 28. Write the functions of FSH and LH. 29. Give detailed note on chemical nature and functions of Insulin. 30. Explain the functions of any one hormone of adrenal medulla. 31. Write the causes and symptoms of conn’s syndrome SECTION –C (3X10=30) Answer any THREE of the following: 32. Write essay on feedback regulation of hormone secretions. 33. Illustrate and explain cAMP cascade of mechanism of hormone action. 34. Explain the functions of posterior pituitary hormones. 35. Write essay on abnormalities of thyroid gland hormones. 36. Explain the abnormalities of adrenocortical function.

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