MANE-001 : HUMAN GENETICS Time : 3 hours Maximum Marks : 100 Note : Answer any five questions. Choose at least two questions from each section. All questions carry equal marks. The word limit for 20 marks is 500 words and for 10 marks are 250 words. SECTION-A
1.
Discuss the importance of human genetics in physical anthropology. Examine briefly the different branches of human genetics.
2.
What is Hardy - Weinberg Law ? What are the 20 different factors that influence change in gene frequencies over a period of time ? Discuss any two factors.
3.
What is Genetic Polymorphism? Examine briefly 20 various tools used for studying polymorphism.
4.
Discuss briefly the Mendel's Laws of inheritance. 20
5.
Write notes on any two of the following : (a) Alkaptonuria (AKP) (b) Consanguineous marriages (c) One gene one enzyme hypothesis (d) Genomics
MANE-001
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20
10+10
P.T.O.
SECTION-B 6.
Define DNA Polymorphism. Describe briefly any two techniques used in Molecular Genetics.
20
7.
What is Human Genome project ? Examine any two applications of Human Genome project.
20
8.
What is Genetic Screening and Genetic Counselling ? Discuss.
20
9.
What do you understand by Bio-informatic. Briefly discuss few tools used in Bio-informatics.
20
10.
Write short notes on any two of the following in 250 words each. 10+10 (a) DNA Structure (b) Hap Map Project (c) Ethical , Legal and Social Issues (ELSI) in Genetics. (d) Balanced polymorphism
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