St. Joseph’s College of Arts & Science (Autonomous) St. Joseph’s College Road, Cuddalore – 607001 PBC805 – MOLECULAR BIOLOGY
Time : 3 hrs
Max Marks :75 SECTION – A (25X1=25) Answer ALL Questions
I. Choose the correct answer 1. The enzyme responsible for initiating DNA replication in prokaryotes is a. DNA Polymerase I b. DNA Polymerase III c. Polymerase beta d. Primase 2. Which out of the following is an inhibitor of prokaryotic transcription? a. Ciprofloxacin b. Etoposide c. Erythromycin d. Rifampicin 3. Restriction endonucleases are enzymes – a. Used for joining DNA to cloning vector b. That cleave randomly c. That digest DNA from ends d. Cleave DNA at specific sites 4. Promoters for tRNAs are located a. Upstream from the start codon b. Downstream from the start codon c. Both (a) and (b) d. None of these 5. Transcription factors are a. Promoters b. Proteins which bind to DNA and regulate transcription c. TATA boxes d. CATT boxes
~1~
Q8/19A/10-14 6. The accepted hypothesis for DNA replication is a. Conservative theory b. Dispersive theory c. Semi-conservative theory d. Evolutionary theory 7. Messelsen and Stahl model of replication was called a. Conservative replication b. Semi-conservative replication c. Dispersive replication d. Cri du Chat 8. The haploid set of the chromosomes is called as a. Proteome b. Genomics c. Genome
d. Genes
9. A functional chromosome has a. A centromere c. An origin of replication
b. A telomere d. All of these
10. Dimer repair mechanism include a. Excision repair c. Recombinational repair
b. Photoreactivation d. All of these
II. State true or false 11. The mutation which will not affect the length of a protein is missense mutation. 12. The enzyme that catalyses the synthesis of DNA is called DNA polymerase. 13. AUAUA is the usual sequence of a pribnow box. 14. DNA polymerase is necessary for transcription to occur. 15. Ligase is not necessary componenet of translation. III. Answer in a sentence on two sentences 16. What is Satellite DNA? 17. Define cot Value. 18. What are Type II topoisomerases? 19. What are Physical mutagens?
~2~
Q8/19A/10-14 20. Name the inhibitors of transcription. 21. Define Wobble hypothesis. 22. What are the characteristics of genetic code? 23. Define Primer. 24. Define exons. 25. Define gene. SECTION – B (5X4=20) Answer any FOUR Questions 26. Explain Griffith experiment. 27. Write a detailed note on organization of genes. 28. Write notes on RNA polymerases. 29. Explain the post translational modifications of proteins. 30. Write a note on gene amplification. 31. Describe the positive and negative regulation of lac operon. SECTION – C (3X10=30) Answer any THREE Questions 32. Discuss the experiments of Griffith, Mcloed, Mccarty and Averty. 33. Explain the steps involved in RNA synthesis. 34. Write an essay on chromosomal aberrations. 35. Discuss Operon concept. 36. Elaborate on protein synthesis.
The enzyme responsible for initiating DNA replication in. prokaryotes is. a. DNA Polymerase I b. DNA Polymerase III. c. Polymerase ... Messelsen and Stahl model of replication was called. a. ... Displaying MOLECULAR BIOLOGY 2 - 11 14.pdf.
What is axoneme? 14. What is Laminin? 15. Define oncogenes. SECTION B (5x4=20). Answer ALL the questions. 16. a) Explain the structure of nucleus. (Or).
Write about the secondary structure of RNA molecule. 2. What are the properties that makes DNA as repository of. information? 3. State the three models of DNA ...
a) Regulator b) Constitutive c) Suppressor d) Repressor. 4. Which of ... Say true or false (5X1=5). 6. ... Displaying MOLECULAR BIOLOGY 2 - 04 16.pdf. Page 1 ...
Head Office : 7361, RAM NAGAR, NEW DELHI - 110 055. Phones : 23672080-81-82; Fax : 91-11-23677446. Shop at: ... Phone : 0141-2709153 ... system or transmitted, in any form or by any means, electronic, mechanical, photocopying,.
... Molecular Biology, Evolution and Ecology by Verma, Agarwal.pdf. Cell Biology, Genetics, Molecular Biology, Evolution and Ecology by Verma, Agarwal.pdf. Open. Extract. Open with. Sign In. Main menu. Displaying Cell Biology, Genetics, Molecular Bio
Michel Morange was trained in biochemistry and molecular biology at the Pasteur Institute in. Paris. His main interests are in the history and philosophy of science and the transformation of biology during the 20th century, in particular the rise of
Introduction to Computational molecular biology - Carlos Setubal, Joao Meidanis.pdf. Introduction to Computational molecular biology - Carlos Setubal, Joao ...
a) 0 b) P/(2Ï) c) P/(4Ï) d) Pm2. /(4Ï. 2. ) 5. Determine the commutators of the operators d/dx and 1/x,. a) -1 b) 2. 1. x. â c) 2. 1. x. d) 2. x. Reg. No. Page 1 of 6 ...