Contribution to SBGN contest: best SBGN map - breadth, accuracy, aesthetics
SBGN-PD map of the main parts of the TGF signalling pathway Katja Wegner Cooperative State University Baden-Wuerttemberg Erzbergerstraße 121 D-76133 Karlsruhe, Germany
The signaling starts after binding of the ligand to the receptors at the membrane. The active receptor complex is able to phosphorylate the receptor-activated Smads. The phosphorylated Smads build a complex with the common Smad4. The complexes translocate to the nucleus to activate or repress genes. The map shows the enhancing of the production of the inhibitory Smad7. Smad7 binds to the active receptor on the same binding side as the receptor-activated Smads to inhibit their phosphorylation.
Acknowledgment: I would like to thank Nicolas Le Novère for hints to include all aspects of SBGN.
SBGN-PD map of the main parts of the TGFβ signalling pathway - GitHub
The signaling starts after binding of the ligand to the receptors at the membrane. The active receptor complex is able to phosphorylate the receptor-activated ...
Dec 2, 2009 - proteins, metabolic network and regulatory network of an organism. This article provides ... INTRODUCTION. Pathway Tools [1â3] is a software environment for .... services including a genome browser, visualization of single ...
5 Export the model image in SVG or PDF format. 5. Export the model image in ... PDF format. 6. Adjust the detail settings of the model using Illustrator. ... Page 10 ...
