The  Mount  Sinai  Medical  Center     The   fellowship   in   Liver   Pathology   is   a   one-­‐   to   two-­‐year   program   providing   in-­‐depth   training   in   liver   pathology   combined   with   research.   The   program   has   been   in   existence   since   1991,   with   graduates   attaining   international   recognition   in   the   filed,   as   well   as   leading   positions   at   prestigious  medical  institutions  in  the  United  States  and  abroad.     The   clinical   portion   of   this   program   is   based   at   The   Mount   Sinai   Medical   Center.   The   fellow   is   expected  to  spend  approximately  90  percent  of  the  time  in  the  clinical  setting,  with  10  percent  of   the   time   dedicated   to   research.   Interpretation   of   native   and   allograft   liver   specimens   are   included   in  the  fellow's  responsibilities.  To  date,  approximately  2,500  transplants  have  been  performed  at   The  Mount  Sinai  Medical  Center.  Each  patient  requires  approximately  three  post-­‐transplant  liver   biopsies  for  evaluation.  In  addition,  there  are  a  large  number  of  biopsies  performed  in  the  adult   and  pediatric  population  for  various  medical  disorders.     The  fellow  is  supervised  by  three  attending  pathologists,  specialized  in  liver  pathology,  who  rotate   on  the  service  on  a  biweekly  basis.  Evaluation  of  the  fellow's  progress  is  undertaken  every  month.   The  fellow  is  expected  during  a  routine  day  to  examine  the  pathology  slides  for  all  cases  of  the  day   and  write  a  preliminary  diagnosis,  examine,  and  process  the  specimens  received  for  grossing  with   the   residents,   examine   and   discuss   the   slides   for   the   day   with   the   attending   pathologists   in   the   afternoon,   and   write   the   final   diagnoses.   In   addition,   the   fellow   has   teaching   responsibilities   as   follows:   medical   student   teaching   in   the   Liver   Pathology   Laboratories   during   the   Pathology   Course,   at   Mount   Sinai   and   Sophie   Davies   City   College,   and   pathology   resident   teaching   during   grossing,  on  a  daily  basis.     The   fellow   is   also   expected   to   attend   and   participate   in   various   intra-­‐   and   interdepartmental   liver   and   gastrointestinal   conferences,   rounds,   and   other   teaching   exercises.   Every   week   the   fellow   is   expected  to  present  findings  from  the  previous  weeks  liver  surgical  cases  to  the  physicians  at  the   Hepatobiliary   Surgical   conference.   On   a   monthly   basis,   the   fellow   is   expected   to   participate   in   presenting   the   pathology   aspects   at   the   clinico-­‐pathological   correlation   conference.   There   are   several   surgical   pathology   conferences,   which   the   fellow   is   required   to   present   during   the   academic   year.   The   fellow   has   to   organize   also   monthly   unknown   slide   conferences   with   the   pathology  residents.     The  fellow  is  required  to  interpret  frozen  section  biopsies  for  organ  donor  evaluation  during  the   daytime.  Four  blocks  of  one  week  of  late  evening  and  night  frozen  section  call  during  the  academic   year  are  also  included  in  the  fellow's  responsibilities.  The  frozen  section  call  covers  all  late  cases   and  donor  organ  evaluation  for  liver  and  kidney  transplant.     Research   may   be   undertaken   as   part   of   active   interdepartmental   research   programs   aimed   at   understanding   the   pathobiology   and   improving   the   diagnosis   and   management   of   hepatic   diseases.   Areas   of   particular   emphasis   include   hepatitis   B   and   C   infection,   acute   and   chronic   rejection,  and  hepatic  and  bile  duct  malignancies.  There  are  opportunities  to  work  with  research   groups   in   the   Department   of   Pathology   and   other   departments   such   as   the   Transplantation   Institute;   the   Center   for   Immunobiology;   Medicine   and   its   Division   of   Infectious   Diseases;   Pediatrics;   Molecular,   Cell   and   Developmental   Biology;   and   Gene   and   Cell   Medicine.  

  During   the   second   year   of   the   fellowship,   the   fellow   will   have   more   in-­‐depth   research   activities,   which   is   reflected   in   increased   research   time   (10-­‐30   percent).   During   this   time,   the   fellow   will   select  his  or  her  own  projects  and  will  take  advantage  of  the  molecular  pathology  facilities  offered   by  the  Department  of  Pathology  and  the  other  departments  to  advance  the  knowledge  of  this  fast   moving  area  and  to  better  understand  the  pathobiology  of  specific  liver  diseases.     The  clinical  responsibilities  will  also  increase  during  the  second  year.  The  fellow  will  conduct  the   sign-­‐out   session   of   liver   pathology   cases   one   day   a   week   with   the   clinicians   and   the   liver   pathologists.  The  fellow  will  also  review  and  interpret  frozen  sections  of  surgical  liver  specimens,   in   addition   to   those   of   donor   livers,   and   will   not   review   and   offer   pathologic   diagnoses   of   consultation  cases  from  other  medical  centers.     Contact:       Allene  Carter   Phone:  (212)  241-­‐8014   FAX:  (212)  534-­‐7491    

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