(BPH 60112)

3.

BYharmacy Dl<~GREE EXAMINATION, APRIL 201G.

(a)

Explain the working of a compartment tray dryer with the help of a neat diagram.

(b)

Draw a typical drying rate curve, taking free. moisture content on the X axis, and describe its various parts.

Sixth Semester

(Supplementary)

Paper I -

PHARMACEUTICAL ENGINEERING -

Or

II

(Regulation 2012-13)

Maximum: 70 marks

Time: Three hours

1.

(c)

Explain the working of a fluidized bed dryer.

(d)

Discuss the factors affecting the rate of drying in a tray dryer.

(a)

Draw (i) boiling point diagram and (ii) composition vapour pressure relationship diagram, for an ideal binary mixture at constant pressure, Discuss there diagrams.

Answer ALL questions. All questions carry equal marks. 1.

(a)

Explain Fourier's law of heat flow.

(b)

Describe the construction of a single pass tubular heater with the help of a neat diagram. Or

(c)

2.

(a)

Explain the construction, principle and working of multipass heater and double pipe heat interchangers. Explain the construction, principle and working of a horizontal tube evaporator and a long tube vertical evaporator.

Or (b)

Explain the construction, principle and working of a falling film evaporator and a climbing film evaporator.

Or

5.

(b)

Explain with the help of neat diagrams, the working of a filter press and a rotary drum filter.

(a)

Explain Mier's theory of crystallisation.

(b)

Explain the working of a Swenson-Walker crystalliser with the help of a neat diagram. Or

(c)

Explain the working of a extractor. Explain the counter-current extraction.

2

Podbielnaik theory of

(BPH 60112)

(BPH 60312)

B.Pharmacy DEGREE EXAMINATION, APRIL 2016.

(Supplementary)

Sixth Semester

Paper II - PHARMACEUTICAL BIOTECHNOLOGY

(Regulation 2012 - 13)

Time: Three hours

Maximum: 70 marks

Answer ALL questions.

All questions carry equal marks.

1.

(a)

Describe design and working of a fermenter with help of a neat diagram.

(b)

Write the streptomycin.

microbial

production

of

Or (c)

Explain in detail about t he importance of secondary metabolites.

(d)

Write the microbial production of citric acid.

2.

(a)

How do you perform the test for sterility for substances having antimicrobial activity? ­ Explain with examples. Add note on media and methods used in test for sterility as per

5.

(a)

Or

IP. (b)

Or (b)

3.

Explain various factors affecting enzyme kinetics. Add note on 'whole cell immobilization.

Explain the standards sterilization methods and test for sterility of sutures and ligatures.

•

Describe the production of interferons by rDNA technology. Add note on synthetic vaccines.

Write about the following: (a)

Liver preparations

(b)

Human dried plasma.

Dr

4.

(c)

BCG vaccine

(d)

Mantoux test.

(a)

Write the principle and procedure for the microbiological assay of penicillin. Add note on importance of microbial limit tests.

Or (b)

Write the principle and procedure for estimation of insulin in blood serum and the applications of radioimmunoassay.

2

(BPH 60312)

3

(BPH 60312)

(BPH 60512) B.Pharmacy

DI~GREE

:l.

(a)

EXAMINATfON, APRIL 2016.

Or

Sixth Semester

(b)

Discuss in detail about the functions, objectives, location and layout of a hospital pharmacy.

(a)

Explain the composrtion, functions and objectives of Pharmacy and Therapeutic Committee. Add a note on role of PTC in drug safety.

(Supplementary) Paper lTl -

HOSPfTAL AND CLINfCAL PHARMACY

4.

(Regulation 2012-] :3)

Time: Three hours

Maximum: 70 marks

Or

Answer ALL questions. All question carry equal marks. 1.

(a)

Discuss in detail about dispensing methods adopted for inpatients in a hospital.

5.

(b)

Describe the various methods adopted for evaluation of Parenterals. Add a note on laminar air flow.

(a)

Discuss the pathophysiology pharmacotherapy of diabetes.

Or (b)

2.

(a)

Explain in detail about the steps to be followed in patient counseling. Describe the pathopliysiology and pharmacotherapy of Rheumatoid arthritis.

Explain in detail about different types of Drug interactions with suitable examples.

and

Or (b)

Explain in detail about the dispensing of ancillary and controlled substances. Add a note on distribution of alcohols.

Or (b)

Explain the etiology and pathophysiology of Asthma. Add a note on metered-dose aerosol inhaler-s. 2

(BPH 60512)