Q7/19B/11-11

Reg. No

St. Joseph’s College of Arts & Science (Autonomous) St. Joseph’s College Road, Cuddalore – 607001 PBC702-CELL BIOLOGY & MOLECULAR GENETICS Time : 3 hrs Max Marks :75

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SECTION - A (15X1=15) Answer ALL Questions I. Choose the best answer

(5 X 1 = 5)

1. Liposome contains. a) Proteins

b) Micelles

c) Lipid bilayer

d) None

2. Chromosome number retain in ____ type of cell division. a) Mitosis

b) Meiosis

c) Both

d) None

3. Chromosome segregation achieved with the help of a) Intermediate filaments

b) Microtubules

c)Actin

d) None

4. Hyaluronic acid present in a) liver

b) lung

c) joints

d) brain

5. Nerve cells usually in ___ phase. a) G1

b) G2

c) G0

d) S

II. Say true or false

(5 X 1 = 5)

6. Fatty acid synthesis occurs in smooth endoplasmic reticulum. 7. Nanotechnology field developed with the help of AFM. 8. Actin attached with chromosomes during cell division. 9. Small molecules transferred through tight junction. 10. Increase in apoptotic activity is responsible for cancer development.

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Q7/19B/11-11

III. Answer in one or two sentences

(5X 1 = 5)

11. Applications of phase contrast microscopy. 12. Define MTOCs 13. What is the type of filaments present in microvilli? 14. Extrachromosomal inheritance 15. Define oncogene SECTION - B (5X4=20) Answer ALL Questions 16. a) Explain the ultra structure of nucleus. (Or) b) Give the functions of ribosomes and peroxisomes? 17. a) Describe briefly about steps in mitosis. (Or) b) Write a note on SEM. 18. a) Illustrate structure and assembly of actin filaments (Or) b) Explain the structure & composition of Flagella. 19. a) Write short notes on cell adhesion molecules. (Or) b) What are chromosomal inheritance abnormalities? 20. a) Briefly explain about programmed cell death. (Or)

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b) Write a note on tumor suppressor genes? SECTION - C (4X10=40) Answer any FOUR Questions 21. Explain about different membrane models. 22. How intracellular organelles are purified? Explain. 23. Write a detailed note on structure and composition of microtubules. 24. Describe in detail about chromosome walking. 25. Write briefly about properties of cancer cells. 26. Explain extra chromosomal inheritance and mitochondrial mutations.

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