HOMEOSTASIS dr. Shofa Nur Fauzah, M.KM FK Unswagati 20 April 2017 Workshop Fisiologi Genetika Guru SMA/SMK/Sederajat Kota-Kabupaten Cirebon

Tujuan Pembelajaran 1. Pengertian homeostasis 2. Mekanisme homeostasis 3. Macam-macam homeostasis 4. Sistem organ yang terlibat dalam Homeostasis

HOMEOSTASIS ? Yunani : homeo (sama) stasis (mempertahankan keadaan) Usaha tubuh untuk mempertahankan keadaan lingkungan didalam tubuh terhadap perubahan lingkungan dalam dan luar tubuh. Claude Bernard : Dengan mempertahankan lingkungan dalam yang relatif stabil, organisme multisel yang kompleks dapat hidup bebas di lingkungn luar yang sangat bervariasi.

Keadaan apa yang harus dipertahankan ? • Suhu tubuh

• Tekanan darah • PH darah • Konsentrasi O2 dan CO2

• Osmoregulation-keseimbangan cairan tubuh • Gula darah

Bagaimana kerja homeostasis ? 4 Postulat yang mendasari homeostasis : 1. Peran sistem syaraf dalam mempertahankan kesesuaian lingkungan dalam kehidupan 2. Kegiatan pengendalian yang bersifat tonik 3. Kegiatan pengendalian yang bersifat antagonis 4. Sinyal kimia dapat mempunyai pengaruh berbeda di jaringan yang berbeda

Cara pengendalian fungsi sel : Komunikasi antar sel secara lokal (intrinsik) dan keterlibatan sistem saraf dan endokrin (ekstrinsik) melalui umpan balik

Umpan balik

Osmoregulasi

Kesembangan Asam Basa PCO2, HCO3 dan PH Asidosis

HCO3 P CO2↓

HCO3 PCO2

Alkalosis

HCO3↑ P CO2

HCO3 PCO2 ↑

Food for thought… • On average, how many organ systems are

involved in each of the processes we’ve explored?

• Are there any organ systems that you see in

all of these processes? • What might happen to these pathways if just

one system was not functioning properly?

Homeostasis ppt.pdf

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