PABLO R MOYA ACADEMIC July 2006 - : Visiting Fellow, Lab of Clinical Science, National Institute of Mental Health, NIH, Bethesda, MD, USA. Postdoctoral studies in neuropharmacology and genetic psychiatry of anxiety disorders. September 2005- June 2006: Postdoctoral position, Lab Cell and Molecular Neurobiology, Prof. Manuel Kukuljan, ICBM, Faculty of Medicine, Universidad de Chile. 2001-2006: Ph.D. in Biomedical Sciences, Faculty of Medicine, Universidad de Chile. Thesis “Assessment of 2,5-dimethoxy-4-Xphenylalkylamines as 5-HT2A/2C ligands with regard to PLA2 activation”, under the supervision of Prof. Bruce K. Cassels, approved with maximal distinction. April 2002: International School of Biophysics A. Borsellino, 33rd Workshop: “Excitability, Secretion and Transport: Molecules to Medication” Ettore Majorana Foundation, Sicily, Italy 1999: Universidad de Santiago de Chile, Professional Title of Biochemist. 1998-1999: Undergraduate thesis: “Development of biofilm biosensors”, under the supervision of Prof. David S. Holmes. 1998: Universidad de Santiago de Chile, Faculty of Chemistry and Biology. B.Sc. in Biochemistry. AWARDS July 2004: Travel Award from Serotonin Club, to attendance at Serotonin Satellite Meeting, 4th Congress of the Federation of European Pharmacological Societes (EPHAR), Porto, Portugal. 2001-2005: Graduate (Ph.D.) scholarship Millennium Institute for Advanced Studies in Cell Biology and Biotechnology, Chile. January 2000: Dr. Alberto Zanlungo Foundation Award, for outstanding scholastic achievement. January 2000: Faculty of Chemistry and Biology Award, as the best student of the class of ´99.

WORK 1995. Universidad de Santiago de Chile, Faculty of Sciences. Teaching assistant in General Chemistry. 1996. Universidad de Santiago de Chile, Faculty of Engineering. Teaching assistant in Organic Chemistry. 1997 and 1998: Universidad de Santiago de Chile, Faculty of Chemistry and Biology. Teaching assistant in Biology I. May 1997-September 1999: Universidad de Santiago de Chile. Faculty of Chemistry and Biology. Molecular Microbiology Lab. Research assistant, Prof. David S. Holmes in charge. CIMM-ICA and DICYT-USACH Grants. April-July 1998: Chile Brewery S.A., Bemberg Group. Professional Practice: Characterization of industrial liquid wastes, for the design of microbiological treatment building. November 1999-March 2001. Universidad Católica de Chile. Biological Sciences Faculty. Research assistant, Pharmacology Lab, Prof. Juan Pablo Huidobro-Toro. Molecular biology studies on the purinergic receptors of human placenta; electrophysiological studies with 5-HT2 receptors expressed in X. laevis oocytes. June-August 2003 and October-December 2004: Health Science Center at San Antonio, University of Texas. Neuropharmacology Lab, Dr. William P. Clarke, in the framework of Ph.D. thesis.

CONFERENCES AND MEETINGS July 2004: Serotonin Satellite Meeting (4th EPHAR Congress), Porto, Portugal, “Hallucinogenic amphetamines and phenethylamines have different pharmacological profiles: in vitro and in vivo studies” Moya P., Sáez P., Reyes-Parada M., Berg K.A., Clarke W.P., and Cassels B.K. Fundamental and Clinical Pharmacology 2004, S1, 145. November 2003: XXV Congress of the Pharmacological Society of Chile, Tomé, Chile, “p-methylthioamphetamine and its N-methylated derivatives induce 5-HT release on rat lateral septum”. Sotomayor R., Moya P., ReyesParada M., Hurtado-Guzmán C, Iturriaga-Vasquez P., Forray M.I., and Gysling K.

November 2000. Serotonin: From the Molecule to the Clinic (official satellite to the 2000 meeting of the Society for Neuroscience) New Orleans, LA, USA. “Differences in the mode of action of psychotropic phenethylamine / phenylisopropylamine pairs on cloned 5-HT2A and 5HT2C receptors”, Acuña-Castillo C., Moya P.R., Cassels B.K., HuidobroToro J.P. and Sáez P. November 2000: 1st Argentine-Chile Meeting in Mendoza, Argentina, “mRNA`s encoding P2X receptors detected in human chorionic vessels” Moya P., and Huidobro-Toro J.P. November 1999: XLII Congress of the Chilean Society of Biology, Pucón, Chile. “Copper and Mercury detection by bioluminescent biosensors”, Moya P., Holmes D. and Ramos M May 1998: Annual Meeting of the American Society of Microbiology, Atlanta, GA, USA. “The use of a biosensor to measure the bioavailability of copper in environmental and food samples", Holmes D., Moya P. and Ramos M. PUBLICATIONS Moya PR, Wendland JR, Kruse M, Ren-Patterson RF, Jensen CL, Cromer KL and Murphy DL. “FUNCTIONAL INTERACTION OF RS25532 WITH THE 5-HTTLPR AND HAPLOTYPIC ASSOCIATION OF THESE AND OTHER NON-CODING FUNCTIONAL SLC6A4 VARIANTS WITH OBSESSIVECOMPULSIVE DISORDER” Human Mol. Genetics (under review)

Moya PR, Berg KA, Gutierrez-Hernandez MA, Saez-Briones P, ReyesParada M, Cassels BK, Clarke WP. “Functional Selectivity of Hallucinogenic Phenethylamine and Phenylisopropylamine Derivatives at Human 5-HT2A and 5-HT2C Receptors” (2007). J Pharmacol Exp Ther. 321(3):1054-61 Valdecantos P., Briones R., Moya P., Germain A., and Huidobro-Toro J.P. “Pharmacological identification of P2X(1), P2X(4) and P2X(7) nucleotide receptors in the smooth muscles of human umbilical cord and chorionic blood vessels” (2003). Placenta 24(1):17-26. Acuña-Castillo C., Villalobos C., Moya P.R., Sáez P., Cassels B.K., and Huidobro-Toro J.P. “Differences in potency and efficacy of a series of phenylisopropylamine / phenylethylamine pairs at 5-HT2A and 5-HT2C receptors” (2002). British Journal of Pharmacology 136, 510-519.

pablo r moya

Chile. “Copper and Mercury detection by bioluminescent biosensors”,. Moya P., Holmes D. and Ramos M. May 1998: Annual Meeting of the American Society of ...

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