INVENTOR TOOK ZIGZAG PATH TO DESTINY | UCLA
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INVENTOR TOOK ZIGZAG PATH TO DESTINY WENDY SODERBURG | March 21, 1999 More Faculty + Staff
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A man of inner vision /UCLAToday Staff Priest, boxer, scientist ... Michael Phelps tried them all before settling on the field of medicine. And the world is lucky he did.
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Phelps invented the positron emission tomography (PET) scanner, an imaging system that provides the means to watch and measure biochemical processes of the human
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body. For this, and for a lifetime of achievement in the field of nuclear science, President Clinton named Phelps a winner of the Enrico Fermi Presidential Award, the government's oldest science and technology prize. "I am deeply honored to receive this award," said Phelps, who will travel to Washington, D.C., next month to receive a gold medallion and a $100,000 honorarium from U.S. Secretary of Energy Bill http://newsroom.ucla.edu/stories/990322inventor[3/10/2017 12:04:17 AM]
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INVENTOR TOOK ZIGZAG PATH TO DESTINY | UCLA
Richardson. Phelps, who serves as the Norton Simon Professor, chair of the Department of Molecular and Medical Pharmacology, director of the Crump Institute for Biological Imaging, associate director of the UCLA/DOE Laboratory of Structural Biology and Molecular Medicine and chief of nuclear medicine, wasn't even considering a career in medicine when he was growing up in a poor, Irish Catholic
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"I wanted to do something that was respected by the community — either a priest or a fighter," Phelps recalled. "I went to the seminary for a few months, but didn't have a calling for it. So I became a boxer."
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At the age of 21 he suffered a head injury in a car accident, so he decided to go to college. He received degrees in math and chemistry from Western Washington University in Washington state and a Ph.D. in chemistry at Washington University in St. Louis. While an assistant professor at the Washington University medical school in 1973, Phelps and his postdoctoral student, Edward Hoffman, created the first PET scanner using old parts and equipment borrowed from a nuclear instrumentation company called ORTEC. In 1974, Phelps and Hoffman built the first PET scanner for human studies. The next year Phelps sold the rights to PET back to ORTEC in thanks for their support; with partners from ORTEC he started a company, Computer Technology and Imaging (CTI), to produce PET scanners. In 1976, Phelps brought his expertise and boundless energy to UCLA and built the leading PET program in the world, both in research and clinical practice. PET scanners use molecules that are labeled with trace amounts of radioactive elements and are then injected into the bloodstream. These molecules send signals back to the PET scanner, which takes
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real-time "pictures" of the biological processes of all the organ systems in a single examination.
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INVENTOR TOOK ZIGZAG PATH TO DESTINY | UCLA
Recently, Phelps received some exciting news: His longtime friend, Senator Ted Stevens (R-Alaska), working with the Secretary of Health and Human Services, announced Medicare coverage of PET scans for heart disease and cancer with a commitment to evaluate other diseases. "I am as enthusiastic about PET today as I was at its inception — in fact, more so," Phelps said. "Biology and genetics are producing
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of this new molecular medicine."
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revolutionary changes in medicine. PET is providing biologicalimaging exams to help detect, understand and treat disease as part
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Head injuries can alter hundreds of genes and lead to serious brain diseases, UCLA biologists report
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