Product Data Sheet Recombinant Human Eotaxin / CCL11 Catalog Number: 100-178
Product Description_____________________________________________________________________ Alternate Names: CCL11, Eosinophil chemotactic protein Accession Number: P51671 Description: Eotaxin, also known as Eotaxin-1 and CCL11, is a chemokine that recruits eosinophils to sites of allergic inflammation. Eotaxin signals through the G protein-coupled chemokine receptors CCR2, CCR3, and CCR5. Eotaxin also negatively regulates adult neurogenesis, and high Eotaxin levels are associated with impaired learning and memory. Source: Genetically modified E.coli. Predicted MW: Monomer, 8.4 kDa (with 74 amino acids) AA Sequence: GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Specifications*__________________________________________________________________ *Lot-specific values for the following specifications are supplied with each production lot on its corresponding COA.
Specification Purity Endotoxin
Method of Determination Reducing and Non-Reducing SDS-PAGE Kinetic LAL (50% confidence)
Acceptance Criteria ≥ 95% ≤ 1 EUs/µg
Product Preparation and Storage__________________________________________________________ Country of Origin: USA Shipping: Room temperature Storage Prior to Reconstitution: -20°C Product Reconstitution: Sterile water at 0.1 mg/mL Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Expiration Date: 12 months from date of receipt when stored at -20°C to-80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed. THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS!
negatively regulates adult neurogenesis, and high Eotaxin levels are associated with impaired learning and memory. Source: Genetically modified E.coli.
Description: Interleukin 16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for. lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression. of the interl
1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed. THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS! Page 1 of 1. Human NGF-beta Data Sheet 100-38
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