Product Data Sheet Recombinant Animal-free Human VEGF-165 Catalog Number: 100-44AF
Product Description_____________________________________________________________________ Alternate Names: VEGF-A, VPF, glioma-derived endothelial cell mitogen Accession Number: P15692-4 Description: Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis. Source: Genetically modified E.coli. This product is produced with no animal-derived raw products. All processing and handling employs animal-free equipment and animal-free protocols. Predicted MW: Dimer, 19.3/38.6 kDa (with 166/332 amino acids) AA Sequence: MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQENPCGP CSERRKHLFV QDPQTCKCSC KNTDSRCKAR QLELNERTCR CDKPRR
Formulation: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Specifications*__________________________________________________________________ *Lot-specific values for the following specifications are supplied with each production lot on its corresponding COA.
Method of Determination Reducing and Non-Reducing SDS-PAGE Kinetic LAL (50% confidence) HUVEC proliferation
Acceptance Criteria ≥95% ≤1 EUs/µg ED50 ≤10 ng/mL(≥ 1.0 x 10^5 units/mg) (typical ED50 is < 5 ng/mL)
Product Preparation and Storage__________________________________________________________ Country of Origin: USA Shipping: Room temperature Storage Prior to Reconstitution: -20°C Product Reconstitution: Sterile water at 0.1 mg/mL Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Expiration Date: 12 months from date of receipt when stored at -20°C to-80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed. THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS!
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Description: Interleukin 16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for. lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression. of the interl
1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed. THIS PRODUCT IS FOR RESEARCH USE ONLY AND IS NOT FOR USE IN HUMANS! Page 1 of 1. Human NGF-beta Data Sheet 100-38
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negatively regulates adult neurogenesis, and high Eotaxin levels are associated with impaired learning and memory. Source: Genetically modified E.coli.
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