Q7/19J/11-14 Reg. No

St. Joseph’s College of Arts & Science (Autonomous) St. Joseph’s College Road, Cuddalore – 607 PBC701S – BIOORGANIC CHEMISTRY

Time : 3 hrs

MaxMarks :75 SECTION –A (15X1=15) Answer ALL Questions

I. Choose the best Answer 1. Name the polysaccharide which cannot have the β-glycosidic linkage a) Cellulose b) Chitin c) Hyaluronic acid d) Heparin 2. Which of the following amino acid is never found in α - helix? a) Leucine b) Proline c) Methionine d) Valine 3. The other name of phosphatidyl choline is a) Lecithin b) Lignocerin c) Cephalin d) None of the above 4. Bond which hold the two DNA strands together a) Hydrogen bond b) Glycosidic bond c) Phosphodiester bond d) All the above 5. Which of the following is the most common class of zinc finger? a) Cys2His2 b) Zn2/Cys6 c) Zinc ribbon d) TAZ2 II. Say true or false 6. Cellulose acts as food reserves in the storage organs of plants 7. Proteins have an axial ratio of <10 are known as globular proteins 8. Acid hydrolysis of waxes yields glycerol and fatty acids

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Q7/19J/11-14 9. The backbone of DNA is formed of nitrogenous bases 10. In Cys2His2, the zinc ion is coordinated by two histidine and two cytidine residues III. Answer in one sentence 11. What are heteroglycans? 12. Define prosthetic group. 13. How fats and oils are differentiated chemically from waxes? 14. Differentiate a nucleoside from nucleotide. 15. What is a zinc finger? Mention its role. SECTION – B (5X4=20) Answer ALL Questions 16. a) Give an account on fructans. (or) b) Give a brief account on glycoproteins and their importance. 17. a) Comment on the importance of Ramachandran plot. (or) b) Write an account on collagen triple helix. 18. a) Give a brief account on classification of lipids. (or) b) Describe the composition, types and functions of lipoproteins. 19. a) Explain the characteristic features of different forms of DNA. (or) b) Write a short note on DNA supercoiling and linking number?

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Q7/19J/11-14 20. a) Write short notes on bHLH motif. (or) b) Explain the importance of DNase I footprinting. SECTION – C (4X10=40) Answer any FOUR Questions 21. Explain the structure and biological importance of any two glycosaminoglycans. 22. Give an account on bacterial cell wall polysaccharide and blood group antigens. 23. Describe the various structural organizations of proteins. 24. Give a detailed account on structure and functions of phospholipids. 25. What are nucleic acids? Describe the primary structure of nucleic acids. 26. Explain in detail on various DNA binding domains and their importance.

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