Code No: 45025

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III B.Tech I Semester Regular Examinations,Nov/Dec 2009 BIOFLUIDS AND MECHANICS Bio-Medical Engineering Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks ????? 1. Differentiate: (a) Soft tissues and hard tissue.

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(b) Tendon in tension. (c) Cartilage and bone.

[5+5+6]

2. (a) Explain in detail the laminar and turbulent flow properties of blood in blood vessels.

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(b) Discuss the flow behavior of blood as it flows through aorta to vena cava. [8+8] 3. Explain the chemical and physical properties of blood and explain the effect of shear stress and hematocrit value on the viscosity of blood. [16]

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4. (a) With the help of a P-V curve of a lung, explain the normal breathing mechanism. (b) What are the lung mechanical parameters? Differentiate normal and abnormal respiratory states. [8+8] 5. Describe the mechanical properties: (a) Synovial fluid. (b) Protoplasm.

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(c) Mucus.

(d) Saliva.

[4+4+4+4]

6. (a) Discuss about the histology and mechanical properties of bone with examples. [8+8]

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(b) Write short notes on Arthritis, Avascular necrosis, Osteoporosis.

7. (a) Write a short note on steady and unsteady flow. (b) Determine the intensity of shear of oil having viscosity 0.1 Ns/m2. The oil is used for lubricating the clearance between a shaft of diameter 0.1m and its journal bearing. The clearance is 1.5mm and the shaft rotates at 150 r.p.m [4+12]

8. (a) Discuss about the motion of red blood cells in tightly fitted tubes (b) Discuss about the inversion of the FAHRAEUS-LINDQUIST effect in very narrow tubes. [8+8] 1

Code No: 45025

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Code No: 45025

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1. (a) Explain briefly the distribution of RBC in narrow tubes.

[8+8]

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(b) Explain FAHRAEUS-LINDQUIST effect.

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III B.Tech I Semester Regular Examinations,Nov/Dec 2009 BIOFLUIDS AND MECHANICS Bio-Medical Engineering Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks ?????

2. (a) Discuss briefly on composition and structure of articular cartilage and meniscus. (b) Briefly explain the functions of meniscus.

[8+8]

or

3. (a) What are differences between solids and liquids? State Hooke’s law. Using stress- strain curve define elasticity.

(b) Define the terms: normal stress, normal strain, shear stress and shear strain. [8+8] 4. (a) Discuss about the composition and mechanical properties of collagen fibres.

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(b) Write a short note on the terms viscoelasticity and pseudo-elasticity critically? [8+8] 5. (a) Describe the process of airway mechanics. (b) List any five lung diseases and explain the causes for development of diseases. [8+8]

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6. Discuss about yield stress of blood. Which factors control the yield stress of blood? Justify that blood behaves like a Cassons fluid. Discuss the characteristics of blood plasma. [16] 7. (a) Differentiate between viscoelastic and elastic materials.

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(b) Explain and derive the expressions for stress-relaxation and creep of a Kelvin model. [4+12]

8. (a) Discuss the flow behavior of blood as it flows through aorta to vena cava. (b) Write a short note on mechanical heart valves. ?????

3

[8+8]

Code No: 45025

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III B.Tech I Semester Regular Examinations,Nov/Dec 2009 BIOFLUIDS AND MECHANICS Bio-Medical Engineering Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks ????? 1. Write briefly about the inversion of the FAHRAEUS-LINDQUIST effect in very narrow tubes. What are the medical applications of blood Rheology? [16]

3. Write a short note on:

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(a) Articular cartilage and meniscus.

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2. State Newton’s law for flow of biological fluids. With reference to laminar flow, define resistance to flow. What are the factors which determine the resistance to flow? [16]

(b) Trabecular Bone and Cortical Bone. (c) Bone Modeling and Remodeling.

[6+5+5]

4. (a) Write a short note on the structure of articular cartilage and meniscus.

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(b) Discuss the mechanical properties of Trabecular Bone Tissue.

[8+8]

5. (a) Describe the construction and working of a Capillary viscometer. (b) Mention the advantages and disadvantages of a Couette viscometer.

[8+8]

6. With relevant sketches, explain the mechanical behavior of arterioles and its physiological significance. [16] 7. (a) Explain the instrument used to test a bio-viscoelastic fluid.

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(b) Using spring and dashpot draw Maxwell model and derive its basic governing equation. [8+8]

8. (a) What do you mean by respiration process? Explain lucidly mechanism of breathing and mechanics of Alveoli?

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(b) Explain why different parts of lungs have difference in ventilation and blood flow. [8+8] ?????

4

Code No: 45025

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III B.Tech I Semester Regular Examinations,Nov/Dec 2009 BIOFLUIDS AND MECHANICS Bio-Medical Engineering Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks ????? 1. Write a short note on :

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(a) Sigma effect. (b) Motion of red blood cells in tightly fitted tubes. (c) Cell-free layer.

[6+6+4]

2. Write a short note on :

(b) Anterior curciate ligament. (c) Histology of tendon.

or

(a) Difference between ligament and tendon.

[5+5+6]

3. (a) Write a short note on air-way resistance?

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(b) Discuss about lung diseases by indicating their cause for development of diseases. [8+8] 4. Describe the Structure and mechanical properties of bone with examples. Explain what do you understand by Lubrication of Joints? [16] 5. (a) Explain the three features of viscoelasticity in detail

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(b) Explain the working principle of oscillating magnetic microrheometer. [8+8] 6. (a) Explain the working of any prosthetic heart valve. (b) Describe the operation of any one mechanical heart valve.

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(c) Compare the performance features of mechanical and tissue heart valves. [6+5+5]

7. Determine the wall shearing stress for a fluid, having a viscosity of 3.5 cP, flowing with an average velocity of 9 cm/s in a 3-mm-diameter tube. What is the corresponding Reynolds number? (The fluid density =1.06 g/cm3) [16] 8. (a) Describe the construction and working of a Couette viscometer. (b) List the advantages of a cone-plate viscometer. ?????

5

[8+8]

R07 Set No - 1

what do you understand by Lubrication of Joints? [16] · 5. (a) Explain the three features of viscoelasticity in detail · (b) Explain the working principle of oscillating ...

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