Universidad Autónoma de Baja California Escuela de Ciencias de la Salud Campus Valle Dorado, Unidad Ensenada Ensenada, Baja California a 28 de Agosto de 2014.

M. D. Margarita Sarlat Sánchez Jefa del Departamento de Cooperación Internacional e Intercambio Académico, UABC Ensenada, B.C Por medio de la presente, envío a ud. el REPORTE DE ACTIVIDADES del intercambio académico que me fue aprobado en la Convocatoria Movilidad Académica 2013-2. Actividad: Asistencia al curso 4th Advanced TB Diagnostic Research course Fecha: 7 al 11 de Julio de 2014 Lugar: McGill University, Montreal, Canada El curso consistió de 40 horas en total, a partir del lunes 7 al viernes 11 de julio del 2014. Al curso asistimos 82 personas de 20 países diferentes. El curso fue impartidos por expertos en el área de la tuberculosis a nivel mundial, representando instituciones educativas, de gobierno, privadas, laboratorios de análisis y representantes de la Organización Mundial de la Salud, Organización Panamericana de la Salud y Center of Diesease Control (CDC). Los principales temas que se trataron durante el curso fueron los siguientes: 1. Global value chain, pipeline, TPPs, TB diagnostics development 2. Market research, incremental value, diagnostic thinking impact, reference standards, patient impact, TB Tech Pitch 3. Implementation research, qualitative research 4. Meta-analysis, GRADE, guidelines, modeling 5. Modeling, cost effectiveness

Durante este curso establecí contacto con muchos de los investigadores que asistieron asi como con los organizadores. En este momento me encuentro en platica con algunos de ellos para someter un proyecto de investigación a la Fundacion Bill and Gates para la convocatoria del 2015.

Así también, me encuentro organizando con apoyo del Cuerpo Académico de Biomedicina, del cual soy líder, un Segundo Simposio de Tuberculosis, teniendo como ponentes a los investigadores que contacté durante el curso. La característica de este Simposio es que las pláticas serán de forma virtual, Escuela de Ciencias de la Salud, Campus Valle Dorado, Unidad Ensenada, Universidad Autónoma de Baja California Blvd. Zertuche y Blvd. de los Lagos s/n. Fracc. Valle Dorado. C.P. 22890. Ensenada, Baja California, México. Tel: 646-1750707 Ext. 65305. [email protected]

   

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utilizando el programa Skype. Hasta el momento tres platicas han sido confirmadas, las cuales serán impartidas en la Sala Audiovisual del Departamento de Información Académica, Unidad Valle Dorado.

Fecha

Investigador

Institución

12-Sep-14

Dra. María Elvira Balcells

Departamento de Enfermedades Infecciosas del Adulto, Pontificia Universidad Católica de Chile Santiago, Chile

19-Sep-14

Dr. Musharaf Tarajia Asvat

INDICASAT-AIP Panamá, Rep. Panamá

Dra. Zulma Vanessa Rueda.

Facultad de Medicina, Universidad Pontificia Bolivariana Bogotá, Colombia

16-Oct-14

Título ponencia Tuberculosis extrapulmonar

Tuberculosis pleural Tuberculosis en cárceles en Colombia: factores de riesgo, diagnóstico y dinámica de transmisión.

El cursó me ha dado más de lo que esperaba, obtuve una gran cantidad de conocimiento, me actualicé en todo el tema del diagnóstico de la tuberculosis a nivel mundial, establecí contacto con una gran cantidad de investigadores que asistieron, y estoy incluida en diferentes listas de avisos y actualización académica de cursos, seminarios, congresos de la tuberculosis a nivel mundial. Este curso lo recomiendo ampliamente a cualquier persona que esté interesada en la línea de investigación de la tuberculosis.

ATENTAMENTE “Por la realización plena del hombre”

Dra. Raquel Muñiz Salazar Investigador-Profesor Escuela de Ciencias de la Salud [email protected]

c.c.p. Dra. Ma. del Socorro Montaño Rodríguez. Coordinadora de Cooperación Internacional e Intercambio Académico. Rectoría Mexicali. c.c.p. Dra. Lynnette A. Velasco Aulcy. Directora. Escuela de Ciencias de la Salud. UABC. c.c.p. Dr. Jesús Córdova Guerrero. Coordinador de Cooperación Internacional e Intercambio Académico. Esc. Cs. Salud. UABC Ensenada. c.c.p. archivo.

Escuela de Ciencias de la Salud, Campus Valle Dorado, Unidad Ensenada, Universidad Autónoma de Baja California Blvd. Zertuche y Blvd. de los Lagos s/n. Fracc. Valle Dorado. C.P. 22890. Ensenada, Baja California, México. Tel: 646-1750707 Ext. 65305. [email protected]

   

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This is to certify that

Raquel Muñiz-Salazar

Universidad Autónoma de Baja California, Mexico

Participated in the 4th Advanced TB Diagnostic Research course held at McGill University, Montreal, Canada from 7 - 11th July 2014 Total course hours: 40

Madhukar Pai, MD, PhD Course Director Associate Professor, McGill University Associate Director, McGill International TB Centre        

 

Hosted by

Venue:

McConnell Engineering Building, McGill University, main campus, 3480 University Street, room 11 Montreal, QC H3A 0E9

COURSE SCHEDULE: OUTLINE Day

Date

Time

Major themes

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July 7, Mon

8.30 AM – 5.30 PM

Global value chain, pipeline, TPPs, TB diagnostics development

2

July 8, Tues

8.30 AM – 4.00 PM

3

July 9, Wed

8.30 AM – 4.00 PM

Market research, incremental value, diagnostic thinking impact, reference standards, patient impact, TB Tech Pitch Implementation research, qualitative research

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July 10, Thur July 11, Fri

8.30 AM – 5.00 PM 8.30 AM – 3.30 PM

Meta-analysis, GRADE, guidelines, modeling Modeling, cost effectiveness

Supported by these partners:

Grant support from:

Course website: www.teachepi.org

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Day 1, July 7, 2014 [Monday] Time 8.00 AM 8.30 – 9.00 AM 9.00 – 10.30 AM 10.30 – 11.00 AM 11.00 – 12.15 PM

Lecture Registration Welcome and Introductions The big picture: global value chain for TB diagnostics Coffee Panel discussion: Scale-up of existing WHO-endorsed tools – country experiences and challenges Moderator: J Creswell

12.15 – 1.00 PM 1.00 –1.50 PM

Lunch Replacing suboptimal tests with WHO-endorsed tests in the Indian private sector Beyond Xpert: fast-followers and NAAT pipeline Coffee Panel discussion: Gaps in the pipeline: priority target product profiles Moderator: M Pai

1.50 – 2.30 PM 2.30 – 3.00 PM 3.00 – 4.15 PM

4.15 – 5.30 PM

5.45 – 6.45 PM

Panel discussion: Can industry fill the gaps? Moderator: J Gallarda

Faculty All M Pai J Kioko Y Pang B Alisjahbana S Tahseen D Rienthong L Vanleeuw H Dabas D Boyle Presenters: C Denkinger & S Kik Discussants: J Gallarda M Casenghi J Creswell A Ramsay S Laal N Engel G Johns M Norman U Ochsner A Suresh B Satterfield M Miller

Wine and Cheese Reception Hosted by McGill International TB Centre Venue: TBA

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Day 2, July 8, 2014 [Tuesday] Time 8.30 – 9.45 AM

Lecture Panel discussion: What is the market for TB diagnostics? Moderator: M Pai

9.45 – 10.45 AM

10.45 – 11.15 AM 11.15 – 12.00 PM 12.00 – 12.45 PM 12.45 – 1.00 PM 1.00 – 1.45 PM 1.45 – 2.30 PM 2.30 – 2.50 PM 2.50 – 4.00 PM

Panel discussion: Optimal reference standards for test evaluation Moderator: M Pai Coffee Diagnostic prediction models and incremental value Lunch Impact of test results on diagnostic thinking Diagnostic RCTs in TB: Same-day smear diagnosis Diagnostic RCTs in TB: Xpert MTB/RIF Coffee Product developers will pitch their product ideas and get candid feedback.

Faculty Presenter: S Kik Discussants: J Gallarda G Johns A Piatek H Dabas C Denkinger Y Pang C Denkinger A Cattamanchi G Theron A Ramsay S Kik M Casenghi S Schumacher M Pai A Ramsay G Theron 1. 2. 3. 4. 5. 6. 7.

Global BioDiagnostics TB Biosciences Alere Inc. Co-Diagnostics HBDC ClaremontBio/KGI CellScope Inc. SomaLogic Inc. 8. BD Diagnostics

Day 3, July 9, 2014 [Wednesday] Time 8.30 – 9.30 AM

Lecture

9.30 – 10.10 AM 10.10 – 10.50 AM 10.50 – 11.15 AM 11.15 – 12.15 PM 12.15 – 1.00 PM 1.00 – 2.00 PM

Implementation research in TB diagnostics: case studies Implementation research in TB diagnostics: case studies Coffee Barriers to POC testing: insights from qualitative research Lunch Xpert MTB/RIF in high incidence settings: TB REACH experience

Panel discussion: Measuring clinical impact: methodological issues and challenges Moderator: S Schumacher

Faculty A Cattamanchi A Ramsay G Theron J Creswell C Denkinger A Cattamanchi A Ramsay N Engel J Creswell 3

2.00 – 2.40 PM

Importance of reproducibility: case study of IGRAs

2.40 – 3.00 PM 3.00 – 4.00 PM

Coffee Panel discussion: Are high burden countries ready for molecular tests? Moderator: A Ramsay

N Banaei (via Skype) VP Myneedu S Tahseen B Kamaldeen S Hossain D Nyehangane R Kingsbury N Ntinginya

Day 4, July 10, 2014 [Thursday] Time 8.30 – 10.00 AM 10.00 – 10.30 AM 10.30 – 11.15 AM

Lecture Systematic reviews of diagnostic accuracy Coffee SR: case study: Xpert for EPTB

Faculty K Steingart

11.15 – 12.00 PM 12.00 – 1.00 PM 1.00 – 2.00 PM 2.00 – 3.15 PM

SR: case study: Predictive value of IGRAs and TST Lunch Guideline development in TB diagnostics Panel discussion: How do countries make policies on new diagnostics? Moderator: M Pai

S Kik

3.15 – 3.45 PM 3.45 – 5.00 PM

Coffee Mathematical modeling: an introduction

S Schumacher

K Steingart J Kioko T Balcha Y Pang U Agarwal B Alisjahbana P Gangadevi D Dowdy

Day 5, July 11, 2014 [Friday] Time 8.30 – 9.30 AM 9.30 – 10.30 AM 10.30 – 10.50 AM 10.50 – 11.50 AM 11.50 – 12.30 AM 12.30 – 1.15 PM 1.15 – 2.30 PM

Lecture Transmission modeling of TB diagnostics Cost-effectiveness analysis of TB diagnostics Coffee Challenges in modeling TB diagnostics Modeling for decision-making Lunch Panel discussion: Linking models to decision-making in public health & policy Moderator: D Dowdy

2.30 – 3.15 PM 3.15 – 3.30 PM

Modeling and cost-effectiveness: a synthesis Course evaluations and closure

Faculty D Dowdy D Dowdy D Dowdy D Dowdy A Piatek J Creswell Y Lema J Kioko A Kritski J Oliwa D Dowdy M Pai

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Course 

  https://goo.gl/maps/hFQba 

  Course:  McConnell Engineering Building    McGill University, main campus    3480 University Street, room 11    Montreal, QC    H3A 0E9    Access: At the corner of University Street and Milton, enter the campus. The McConnell Engineering  Building is the first on the left, and the room (#11) is in the hallway on the left.     

PARTICIPANTS NAME

AFFILIATION

CRESWELL, Jacob DABAS, Harkesh DAVIDS, Malika DE GROOTE, Mary Ann DENKINGER, Claudia DERYNCK, Meaghan DOWDY, David ENGEL, Nora

National Institute of Tuberculosis and Respiratory Diseases (NITRD), India Padjadjaran University, Indonesia Pontificia Universidad Católica de Chile, Chile Ministry of Health, Ethiopia Stanford University, USA University of Rwanda, Rwanda PATH, Seattle, USA Médecins Sans Frontières Access Campaign, Switzerland University of California San Francisco, USA Medical Faculty-Universitas Padjadjaran (MFUNPAD), Indonesia Stop TB Partnership, Geneva, Switzerland Clinton Health Access Initiative (CHAI), India University of Cape Town, South Africa SomaLogic, Inc., USA FIND, Switzerland Results Canada, Ottawa, Canada Johns Hopkins University, USA Maastricht University, The Netherlands

FERNANDES, Priyanka

Boston's Children Hospital, USA

GALLARDA, Jim

Bill and Melinda Gates Foundation, USA National Institute for Research in Tuberculosis/ICMR, Madurai Unit, India McGill University, Canada BRAC, Dhaka, Bangladesh Purbanchal University, Nepal Alere Inc., USA Kinq Fahad Medical City, Saudi Arabia Samrudhi Group, India McGill University, Canada National Tuberculosis Institute, India National Tuberculosis Program, Ministry of Health, Kenya Universidade Federal do Rio de Janeiro, Brazil New York University School of Medicine, USA University of Washington, USA Clinton Health Access Initiative (CHAI), USA National Institute for Medical Research, Tanzania Lahey Health, USA Clinton Health Access Initiative (CHAI), India University of Nairobi/University of Washington, USA McGill University, Canada bioMerieux, France

AGARWAL, Upasna ALISJAHBANA, Bachti BALCELLS, Maria Elvira BALCHA, Taye Tolera BANAEI, Niaz BIRUNGI, Francine BOYLE, David CASENGHI, Martina CATTAMANCHI, Adithya CHAIDIR, Lidya

GANGADEVI, Poorana GHIASI, Marzieh HOSSAIN, Sarder Tanzir JHA, Yogesh JOHNS, Glenn KAMALDEEN, Baba KELAMANE, Santosha KIK, Sandra KINGSBURY, Reena KIOKO, Jackson KRITSKI, Afrânio LAAL, Suman LACOURSE, Sylvia LEAVITT, Melissa LEMA, Yakobo MACMILLAN, Robert MAHESHWARI, Prateek MARANGU, Diana MCDOWELL, Andrew MILLER, Mark

EMAIL [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] .edu [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected]

MOHD HANAFIAH, Khayriyyah (Kye) MUKHOPADHYAY, Bratati MUÑIZ-SALAZAR, Raquel MUNUO, Godwin MYNEEDU, Vithal Prasad NATHAVITHARANA, Ruvandhi NIEMZ, Angelika NORMAN, Michael NTINGINYA, Nyanda

Burnet Institute/Monash University, Australia Translational Health Science & Technology Institute, India Universidad Autónoma de Baja California, Mexico Centers for Disease Control and Prevention, Tanzania National Institute of TB and Respiratory Diseases (RNTCP), India

PARULKAR, Aparna PIATEK, Amy QIN, Zhi Zhen RAMSAY, Andrew RIENTHONG, Dhanida RIGSBY, Erin ROSALES KLINTZ, Senia SANDLUND, Johanna SATTERFIELD, Brent

Co-Diagnostics HBDC, USA

SATYANARAYANA, Srinath SCHUMACHER, Samuel SKANDARAJAH, Arunan SMITH, Liezel

McGill University, Canada McGill University, Canada University of California, Berkeley, USA University of Cape Town, South Africa William Davidson Institute at the University of Michigan, USA Cochrane Infectious Diseases Group, USA BD Diagnostics, USA NTRL, Pakistan INDICASAT-AIP, Panama University of Cape Town, South Africa MRC, Gambia Treatment Action Campaign, South Africa Postgraduate Institute of Medical Education and Research (PGIMER), India Geneva Global, USA Clinton Health Access Initiative (CHAI), India Boston University, USA

VOLPICELLI, Kate WANG, Maria WONG, Sharon

[email protected]

[email protected] [email protected]

SomaLogic, Inc., USA United State Dept. of Defense, Nigeria KEMRI-Wellcome Trust Research Programme Nairobi, Kenya McGill University, Canada Chinese Center for Disease Control and Prevention (CDC), China Clinton Health Access Initiative (CHAI), India USAID, USA McGill University, Canada TDR, WHO, Switzerland National TB Reference Laboratory, Thailand Global BioDiagnostics Corp., USA Karolinska Institute, Sweden Stanford Medical Center, USA

VERMA, Indu

[email protected]

Keck Graduate Institute, USA Global BioDiagnostics Corp., USA NIMR-MBEYA Medical Research Centre, Tanzania

OCHSNER, Urs OGUNDEJI, Damola Amos OLIWA, Jacqueline (Jacquie) PAI, Madhukar

STEINGART, Karen SURESH, Anita TAHSEEN, Sabira TARAJIA ASVAT, Musharaf THERON, Grant TOGUN, Toyin Omotayo VANLEEUW, Lieve

[email protected]

[email protected]

MSF-FRANCE-Epicentre, Uganda

SMITH, Lisa

[email protected]

Beth Israel Deaconess Medical Center, USA

NYEHANGANE, Dan

PANG, Yu

[email protected]

Grant support from:

[email protected] [email protected] g [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] AND [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected]